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Symbol
Name
ID

Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1
MGI:95412

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Increased circulating IgA level	Increased circulating IgG level	Decreased circulating antibody level	Paraproteinemia	Acute lymphoblastic leukemia	T-cell acute lymphoblastic leukemias	Acute myeloid leukemia	Lymphadenopathy	Splenomegaly	Hepatosplenomegaly	Peritoneal abscess
Disease(s) Associated with ERCC1	Increased circulating IgA level	Increased circulating IgG level	Decreased circulating antibody level	Paraproteinemia	Acute lymphoblastic leukemia	T-cell acute lymphoblastic leukemias	Acute myeloid leukemia	Lymphadenopathy	Splenomegaly	Hepatosplenomegaly	Peritoneal abscess
acute lymphoblastic leukemia
acute myeloid leukemia
multiple myeloma
pancreatic cancer

Mouse Phenotypes		decreased B cell proliferation	abnormal class switch recombination	abnormal spleen morphology	spleen hypoplasia
Availability	Mouse Genotype	decreased B cell proliferation	abnormal class switch recombination	abnormal spleen morphology	spleen hypoplasia
	Ercc1^tm1Jhjh/Ercc1^tm1Jhjh
	Ercc1^tm2Jhjh/Ercc1^tm2Jhjh

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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